immunogenetr: A Comprehensive Toolkit for Clinical HLA Informatics
A comprehensive toolkit for clinical Human Leukocyte Antigen (HLA) informatics, built on 'tidyverse' <https://tidyverse.tidyverse.org/> principles and making use of genotype list string (GL string, Mack et al. (2023) <doi:10.1111/tan.15126>) for storing and computing HLA genotype data. Specific functionalities include: coercion of HLA data in tabular format to and from GL string; calculation of matching and mismatching in all directions, with multiple output formats; automatic formatting of HLA data for searching within a GL string; truncation of molecular HLA data to a specific number of fields; and reading HLA genotypes in HML files and extracting the GL string. This library is intended for research use. Any application making use of this package in a clinical setting will need to be independently validated according to local regulations.
| Version: |
1.0.1 |
| Depends: |
R (≥ 4.1.0) |
| Imports: |
cli (≥ 1.0.0), dplyr (≥ 1.1.1), glue (≥ 1.8.0), magrittr (≥ 2.0.3), purrr (≥ 1.0.2), rlang (≥ 1.1.2), stringr (≥
1.5.0), tibble (≥ 3.1.3), tidyr (≥ 1.3.0), tidyselect (≥
1.2.0), xml2 (≥ 1.3.6) |
| Suggests: |
testthat (≥ 3.0.0) |
| Published: |
2025-10-23 |
| DOI: |
10.32614/CRAN.package.immunogenetr |
| Author: |
Nicholas Brown 
[cre, aut],
Busra Coskun
[aut] |
| Maintainer: |
Nicholas Brown <nicholas.brown at pennmedicine.upenn.edu> |
| BugReports: |
https://github.com/k96nb01/immunogenetr_package/issues |
| License: |
GPL (≥ 3) |
| URL: |
https://github.com/k96nb01/immunogenetr_package |
| NeedsCompilation: |
no |
| Language: |
en-US |
| Materials: |
README, NEWS |
| CRAN checks: |
immunogenetr results |
Documentation:
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