Package: ISPAT3D
Type: Package
Title: Spatial Conditional Association Networks in Registered Tumor
        Volumes
Version: 0.3.1
Authors@R: person("Sagnik", "Bhadury", email = "bhadury@umich.edu",
    role = c("aut", "cre"))
Description: Fits tumor-zone-specific conditional cell-density networks from
    registered three-dimensional multiplex imaging. An anisotropic
    Matern-3/2 Gaussian process is estimated per variable and zone using a
    Vecchia likelihood on spatially balanced anchors; predictions at all
    selected cells yield residual covariance sufficient statistics.
    Gaussian maximum likelihood then fits a shared-plus-zone factor
    covariance model. A matched section-wise planar fit uses the same
    selected cells and covariance estimator. This extends the spatially
    informed cell-density analysis of Bhadury et al. (2026)
    <doi:10.1038/s41598-026-35341-8>.
License: MIT + file LICENSE
Encoding: UTF-8
Imports: gpboost, graphics, stats, utils
Suggests: data.table, knitr, rmarkdown, testthat (>= 3.0.0)
VignetteBuilder: knitr
URL: https://github.com/sagnikbhadury/ISPAT-3D
BugReports: https://github.com/sagnikbhadury/ISPAT-3D/issues
Config/testthat/edition: 3
Config/roxygen2/version: 8.0.0
NeedsCompilation: no
Packaged: 2026-09-16 15:43:50 UTC; bhadury
Author: Sagnik Bhadury [aut, cre]
Maintainer: Sagnik Bhadury <bhadury@umich.edu>
Repository: CRAN
Date/Publication: 2026-09-27 16:40:37 UTC
Built: R 4.5.2; ; 2026-09-27 19:54:36 UTC; unix
